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Less Common Side Effects Injection site reactions: Usually minor redness or irritation

Dubin, MD, is associate professor at Pennington Biomedical Research Center, Louisiana State University Health Sciences

Use the drug wrong and you can trade fat mass for a smaller, weaker engine

If vitamin B12 deficiency ensues, other types of anemia and neurological damage may result

Long-Term Side Effects Long-term usage of Metoprolol may result in the emergence of specific conditions, including heart block, aggravation of angina symptoms upon sudden discontinuation, or the formation of an antinuclear antibody that can trigger certain autoimmune disorders