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In particular, Bcl-2 and Bcl-xL inhibit apoptosis by maintaining mitochondrial membrane integrity whereas Bax and Bak facilitate apoptosis by initiating the loss of outer mitochondrial integrity [21]

Excessive alcohol use also makes it difficult for your body to absorb nutrients or prevent you from eating enough calories

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Glutaminolysis was also reported to sensitize melanoma cells to ferroptosis (47)

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