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So they do seem to be able to reduce some degree of insulin resistance and promote a more normal production of insulin from the pancreas, and this can often be very disordered in individuals who are using this medication, especially people with Type 2 diabetes, but also people who are using it for issues like obesity because many of those individuals do have insulin resistance that this medication does correct to a certain degree

In the OASIS 1 trial, these endpoints were met and reached statistical significance

T., & Suzuki, K

Mitochondrial dysfunction and oxidative stress in heart disease