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As early as 1961, the president of the American Cancer Society, along with presidents of the National Tuberculosis Association (later the American Lung Association) and others, issued a letter urging President Kennedy to create a commission that would investigate the health hazards of smoking

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As previously mentioned, acrolein and formaldehyde damage the precious cilia, reducing the effectiveness of the lungs defense

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Critics worry the slick packaging and marketing around IQOS seems more geared toward attracting youth than helping wean longtime smokers off cigarettes