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A post-mortem study of human pancreases demonstrated proliferative effects in those cases with GLP-1RA use, which were manifest by an increased mass of the pancreas along with increased frequency of PanIN1 and PanIN2 lesions compared to diabetes controls 23
11 Because GLP-1 medications slow stomach emptying, theres a small risk of food or liquid still being in the stomach when youre anaesthetised, which can be inhaled into the lungs (pulmonary aspiration)
Understanding the long-term nature of treatment is essential, as these medications typically require ongoing use to maintain weight loss
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doi: 10.1016/j.bja.2023.12.015
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