Levels of GHK naturally decline as we age and research has demonstrated that this peptide can stimulate synthesis of collagen, elastin, and glycosaminoglycans in the skin
AOD-9604 holds no Health Canada human or veterinary use authorization, and Health Canada has stated in public advisories that unauthorized injectable peptide products are illegal regardless of the 'for research use only' labelling on the container
However, CYP2D6 also metabolizes a significant number of other commonly used drugs, so that debrisoquine polymorphism remains clinically significant
(12) M Macvanin, Z Gluvic, J Radovanovic, M Essack, et al (2023) New insights on the cardiovascular effects of IGF-1 Frontiers in Endocrinology (Lausanne), 2023 Feb 9, Volume 14, Page 1142644
PMC2757071 Bodart V, Febbraio M, Demers A, et al