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Blood in the stool or black, tarry stools Fever above 101F (38.3C) or chills Signs of dehydration dizziness, dark urine, very little urination, dry mouth, confusion, racing heart Severe abdominal pain or pain that radiates to your back (potential pancreatitis warning) Vomiting that prevents you from keeping fluids down for more than 12 hours Loose stools lasting more than 7 days without improvement Sudden, unintended weight loss greater than 5% of your body weight in a week Severity decoder: watery, liquid, explosive what each means Stool consistency on Zepbound varies widely

Staying hydrated, eating small protein-rich meals, and going slow with dose increases minimize discomfort while keeping progress steady

Individual response varies, and some patients reach plateau weight loss before reaching the maximum dose, making personalized dose optimization essential