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Oh yeah, I definitely avoided saunas when I was pregnant

The increased apoptosis observed was presumably initiated by the altered mitochondrial membrane potential causing release of cytochrome c and activation of the intrinsic apoptotic pathway

Toxics 5 , 5030022 (2017)

Furthermore, M1 macrophage-derived exosomes reduce E-cadherin expression in the intestinal barrier by secreting miR-21a-5p, which exacerbates intestinal inflammation in UC model mice and destroys the structure and function of the intestinal barrier