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3 Results 3.1 Base case analysis Total discounted lifetime costs, life-years (LYs), quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios (ICERs) are presented in Table 4

The more plausible worry is indirect: if oral glutathione alters the gastric micro-environment (for instance, by binding trace minerals in the gut lumen), it could marginally shift the pool of free cations available to complex with alendronate, making absorption even less predictable