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Minimizing Methylmalonic Acid Levels A potential problem with the IOMs method for determining B12 requirements (see Institute of Medicines Recommendations above), is that a small percentage of people with neurological symptoms of B12 deficiency have normal blood parameters, including 13% of patients in one series of case studies (Lindenbaum, 1988)

This condition, called megaloblastic anemia, devastates endurance performance even in its mild forms

The appropriate dose is dictated entirely by the design of the experiment

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