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[66] reported that patients with IBD with NUDT15 variants had significantly higher DNA-TG levels compared with nonvariants, while patients with NUDT15 variants did not have significantly higher 6-TGN levels compared with nonvariants

doi: 10.3390/antiox13030298 Summary Keywords ferroptosis, iron metabolism, lipid peroxidation, neuroinflammation, neurodegenerative diseases, brain disorders Citation Yi Y, Jia P, Xie P, Peng X, Zhu X, Yin S, Luo Y, Deng Y and Wan L (2025) Beyond oxidative stress: Ferroptosis as a novel orchestrator in neurodegenerative disorders

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Advanced technique: Some physicians approve splitting to twice-weekly smaller doses during peak side effect weeks (e.g., two 6mg injections instead of one 12mg)