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In aging-related PD, the number of mitochondrial-lysosomal contacts decreases, and the instability of these contact sites leads to disruption of mitochondrial and lysosomal amino acid homeostasis

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2024;109(3):e1230-e1238

This study clarified the potential mechanism of PFOS-mediated RTC apoptosis and provided a new strategy for using l-Carnitine to prevent and treat PFOS-induced RTC apoptosis