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Immunohistochemistry using serial sections revealed that the vacuolar hepatocytes with accumulation of acrolein adducts were immunopositive for perilipin 2 (Fig

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Iron overload induces the separation of IRP1 from IRE-like sequence, activating NOX4 transcription, increasing lipid peroxidation accumulation, and leading to significant dysregulation of mitochondrial morphology and function of osteoblasts

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