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Tom Gavin Fact-Checker Tom Gavin joined Everyday Health as copy chief in 2022 after a lengthy stint as a freelance copy editor

These findings support use of FSL in adults with T2D treated with GLP-1 RA

Dose Titration Table | Week | Tirzepatide Dose | |------|-----------------| | 1 to 4 | 2.5 mg weekly | | 5 to 8 | 5.0 mg weekly | | 9 to 12 | 7.5 mg weekly | | 13 to 16 | 10.0 mg weekly | | 17 to 20 | 12.5 mg weekly | | 21+ | 15.0 mg weekly (max) | Patients who cannot tolerate a dose increase may stay at the current dose for an additional 4 weeks before attempting the next step

By tweaking the GLP-1 molecules structure (for instance, replacing an amino acid to avoid rapid DPP-4 enzyme degradation and attaching a fatty chain to prolong its circulation time), Novo Nordisk created a molecule that only needs to be injected weekly

Use daily for the best results