Esses medicamentos foram desenvolvidos inicialmente para o tratamento do diabetes tipo 2 , j que ajudam no controle da glicose de forma eficaz e segura
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1,2 These activities are constantly challenged by intrinsic and extrinsic perturbations, including increased protein synthesis, ER-Ca 2+ depletion, dysregulated redox homeostasis, energy deprivation, hypoglycemia, hypoxia, and inflammatory stimuli, resulting in improper protein conformation and misfolding, often referred to as nonnative or aberrant conformation
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